Body Mass Index Trajectories in the First 5 Years and Associated Antenatal Factors

Body Mass Index Trajectories in the First 5 Years and Associated Antenatal Factors

Blog Article

Background: The increasing prevalence of childhood obesity is an important public health issue and the development of obesity in early life and associated Tanks/Jerseys risk factors need to be better understood.The aim of this study was to identify distinct body mass index trajectories in the first 5 years of life and to examine their associations with factors identified in pregnancy, including metabolic parameters.Methods: BMI measurements from 2,172 children in Ireland enrolled in the BASELINE cohort study with BMI assessments at birth, 2, 6, and 12 months, and 2 and 5 years were analyzed.Growth mixture modeling was used to identify distinct BMI trajectories, and multivariate multinomial logistic regression was used to assess the association between these trajectories and antenatal factors.

Results: Three distinct BMI trajectories were identified: normal (89.6%); rapid gain Pulsar in the first 6 months (7.8%); and rapid BMI after 12 months (2.6%).

Male sex and higher maternal age increased the likelihood of belonging to the rapid gain in the first 6 months trajectory.Raised maternal BMI at 15 weeks of pregnancy and lower cord blood IGF-2 were associated with rapid gain after 1 year.Conclusion: Sex, maternal age and BMI, and IGF-2 levels were found to be associated with BMI trajectories in early childhood departing from normal growth.Further research and extended follow-up to examine the effects of childhood growth patterns are required to understand their relationship with health outcomes.